A Bute and Banamine cocktail; are they a prescription for ulcers and gastrointestinal ulceration? According to a study presented by Jonathan Foreman, DVM, MS, Dipl. ACVIM, of the University of Illinois, at the AAEP 2011 convention in San Antonia Texas the answer is yes.
Researchers studied 8 Thoroughbred horse with induces reversible lameness and the therapeutic benefits of Bute or Banamine vs a Bute and Banamine combination.
The horses were fitted with heart bar shoe that used screws to tighten them. This induced non-weight-bearing lameness. The Horses wore the shoes for an hour after which they were treated with Bute, Banamine or both Bute and Banamine to determine the benefits of each.
Researchers concluded that there was no significant benefit to treating a horse with both and in fact may do more harm than good. When used in combination there is an “increased risk of gastrointestinal and renal toxicity” resulting in ulcers and gastrointestinal ulceration.
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